心血管医学研究所—陈唐葶副研究员—硕导
陈唐葶，副研究员，硕士研究生导师，2003-2008年就读于泸州医学院临床医学系，获医学学士学位；2008-2011年就读于南方医科大学病理性与病理生理学，获医学硕士学位。2011-至今就职于西南医科大学心血管医学研究所。雷鸣教授课题组成员。主持国家自然科学基金青年基金项目1项，四川省自然科学基金青年基金项目1项，泸州市科技局自然基金项目1项，横向课题1项；发表SCI研究论文10余篇。主要研究心血管系统重构及其病理生理机制，包括心肌肥厚、心肌梗死、心律失常所致的结构性重构和电重构机制，高血压所致的血管重构和糖尿病血管新生障碍等。
研究方向：
1、心肌纤维化在心肌结构性重构和电重构中的病理生理学机制
2、糖尿病血管新生障碍
招生专业：病理学与病理生理学（100104)
联系方式：E-mail: ctt@swmu.edu.cn
联系地址：西南医科大学城北校区科技大楼202室，646000
科研项目：
1. 国家自然科学基金青年基金项目，AGEs通过RAGE-mDia-1-Src信号通路调控“VEGF抵抗”，项目号：81900277，2020.1.1-2022.12.31，21万，主持
2. 四川省自然基金青年基金项目：新型化合物JB2019A抑制儿茶酚胺敏感性室速的机制研究，项目号：2022NSFSC1602，2022.1.1-2023.12.31，6万，主持
3. 电子科技大学横向合作项目：超声波辐照诱导心肌正性肌力作用的实验研究，2021.7-2022.7，10万元，主持。
4. 羟基红花黄色素A对心肌纤维化的保护作用及其机制研究，2015/07-2018/07，3万元，主持。
发表论文
(1) Zhou Haiyan#, Chen Tangting#, Li Yongjie, You Jingcan, Deng Xin, Chen Ni, Li Tian, Zheng Youkun, Li Rong, Luo Mao, Wu Jianbo*, Wang Liqun*. Glycation of Tie-2 Inhibits Angiopoietin-1 Signaling Activation and Angiopoietin-1-Induced Angiogenesis. Int J Mol Sci. 2022 Jun 27;23(13)
(2) Xian Luo#, Wendie Yu#, Zhu Liu#, Zhaoli Pu, Ting Liu, Yangpeng Li, Weichao Liu, Ming Lei, Xiaoqiu Tan*, Tangting Chen* Ageing Increases Cardiac Electrical Remodelling in Rats and Mice via NOX4/ROS/CaMKII-Mediated Calcium Signalling. Oxid Med Cell Longev. 2022, 2022: 8538296,
(3) Huiying Ren, Zhaoli Pu, Tianyi Sun, Tangting Chen, Leiying Liu, Zhu Liu, Christopher O'Shea, Davor Pavlovic, Xiaoqiu Tan*, Ming Lei*. High-Resolution 3D Heart Models of Cardiomyocyte Subpopulations in Cleared Murine Heart. Front Physiol. 2022;13:779514
(4) Shicheng He#, Kun Kou#, Christopher O'Shea#, Tangting Chen, Razik Mu-U-Min, Ruirui Dong, Huiying Ren, Xiaolin Zhou, Zhongcai Fan, Xiaoqiu Tan, Davor Pavlovic, Xianhong Ou*, Ming Lei*. A dataset of dual calcium and voltage optical mapping in healthy and hypertrophied murine hearts. Sci Data. 2021 Dec 16;8(1):314
(5) Tangting Chen#, Jingling Dong#, Haiyan Zhou, Xin Deng, Rong Li, Ni Chen, Mao Luo, Yongjie Li, Jianbo Wu*, Liqun Wang*. Glycation of fibronectin inhibits VEGF-induced angiogenesis by uncoupling VEGF receptor-2-c-Src crosstalk. J Cell Mol Med. 2020 Aug;24(16):9154-9164.
(6) Tangting Chen, Miaoling Li, Xuehui Fan, Jun Cheng*, Liqun Wang*, Sodium tanshinone IIA sulfonate prevents angiotensin II-induced differentiation of human atrial fibroblasts into myofibroblasts, Oxid Med Cell Longev, 2018, 2018: 6712585.
(7) Jun Cheng#, Tangting Chen#, Jing Wen, Ningbo Pang, Liping Zhang, Liqun Wang*, Sodium tanshinone IIA sulfonate prevents lipopolysaccharide-induced inflammation via suppressing nuclear factor-κB signaling pathway in human umbilical vein endothelial cells, Can J Physiol Pharmacol, 2018, 96(1): 26-31.
(8) Ningbo Pang, Tangting Chen, Xin Deng, Ni Chen, Rong Li, Meiping Ren, Yongjie Li, Mao Luo, Haiyan Hao, Jianbo Wu*, Liqun Wang*, Polydatin prevents methylglyoxal-induced apoptosis through reducing oxidative stress and improving mitochondrial function in human umbilical vein endothelial cells, Oxid Med Cell Longev, 2017, 2017: 7180943.
(9) Tangting Chen, Ni Chen, Ningbo Pang, Lamei Xiao, Yongjie Li, Rong Li, Mao Luo, Xin Deng, Meiping Ren, Jianbo Wu*, Liqun Wang*, Hydroxysafflor yellow A promotes angiogenesis via the angiopoietin 1/Tie-2 signaling pathway, J Vsac Res, 2016, 53(5-6): 245-254.
(10）Liqun Wang#, Tangting Chen#, Xiang Zhou, Qiaobing Huang, Chunhua Jin*, Atomic force microscopy observation of lipopolysaccharide-induced cardiomyocytes cytoskeleton reorganization, Micon, 2013, 51: 48-53.
